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The most common side effects you might experience with Biktary include:. In most cases, these foods simply interact poorly and make the antibiotics less effective. If it upsets your stomach, take it with food. Perfect spa yonkers bmw boost pressure sensor location. You can take it with or without food. These may include: Vomiting Nausea Bloating Abdominal pain. In fact, when Bactrim is administered with food, water, or milk, stomach irritation is often minimized It is recommended that someone drink a full glass of water or two with each dose, as well as plenty of fluids during the course of the day, but it can be taken with or without food. Marjorie zych +0 MA Marvell 3 Jan 2011 It doesn't matter too much whether you take Bactrim with or without food. 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